� it the levels of iep, zn and changed after dialysis, due amoxicillin abnormal dreams to the removal of molecules that were poorly linked mainly amoxicillin abnormal dreams free peg at the outer part of the surface, allowing accessibility to the inner adjacent part of the amoxicillin abnormal dreams shell water shell fig accessible amoxicillin abnormal dreams layer to counter ions amoxicillin abnormal dreams characterized by its thickness x and its dipolar charge density zn nm lnc presented amoxicillin abnormal dreams the bestorganized and the accessible amoxicillin abnormal dreams part of the shell, compared with other sizes of lnc, before and after dialysis lecithin was found to amoxicillin abnormal dreams be present in the inner amoxicillin abnormal dreams part of the polyelectrolyte layer amoxicillin abnormal dreams and was found to amoxicillin abnormal dreams play a role in the amoxicillin abnormal dreams disorganization of the outer part amoxicillin abnormal dreams dialyzing lnc formulated with amoxicillin abnormal dreams lecithin led to stable and amoxicillin abnormal dreams well structured nanocapsules, ready for an in vivo use as a drug delivery system evaluation lithium in the earths crust of complement system activation generally, after intravenous administration, nanoparticles np are rapidly removed amoxicillin abnormal dreams from the blood stream because they are recognized by cells of the mps such as kiipffer cells in the liver, or spleen and bonemarrow macrophages however, a brush of peg chains grafted on the surface is known to decrease the recognition amoxicillin abnormal dreams of nanoparticles by the immune system after intravenous administration one has demonstrated that a amoxicillin abnormal dreams strong correlation prevails between the amoxicillin abnormal dreams complement activation and the stealthy properties of lnc therefore, amoxicillin abnormal dreams these properties were evaluated by measuring the degree of complement activation [ch technique and crossed immunoelectrophoresis c cleavage] and the level of macrophage uptake, in relation to the amoxicillin abnormal dreams organization of peg chains, according to the electrokinetic properties amoxicillin abnormal dreams of the lnc surface these amoxicillin abnormal dreams experiments were performed on , and nm lnc before and after dialysis the ch technique is presented in fig nanoparticles are dispersed in human serum with sensitized erythrocytes after amoxicillin abnormal dreams incubation, lysis is evaluated by a classical spectrophotometric method the measured absorbance is related to the consumption of complement proteins by particles the main conclusions are that whatever the in vitro test, all lnc were not recognized by the non specific components of the immune system amoxicillin abnormal dreams it was probably due to the strong density of peg chains at their surface furthermore, dialysis maintains a sufficiently high density of peg and had no incidence on the complement consumption pharmacokinetic studies and biodistribution at first, the biodistribution of radiolabeled nanocapsules was studied by scintigraphy and � counting, after intravenous administration in drowsiness and aricept rat whereby the mtcoxine was incorporated in the lipid core and i labelled the shell of the nanocapsules dynamic scintigraphic acquisition was carried out hrs after administration and � activity in blood and tissues was followed for more than hrs see fig an early halfdisappearance time of about � min was found for i and � min for mtc these ranges of residence times were interesting for specific �a st active wcd�s amoxicillin abnormal dreams vcub nnnnil scrum cdds vr i ?